Hypokalaemic periodic paralysis: treatment

Evidence-based neurology checklist on hypokalaemic periodic paralysis: treatment: Oral potassium Potassium chloride is preferred The dose is 0.2-0.4mEq/kg every 30 minutes: the maximum dose is 200-250mEq/day It is taken with plenty of water Avoid slow release preparations Intravenous potassium…

Oral potassium

  • Potassium chloride is preferred
  • The dose is 0.2-0.4mEq/kg every 30 minutes: the maximum dose is 200-250mEq/day
  • It is taken with plenty of water
  • Avoid slow release preparations

Intravenous potassium

Potassium sparing diuretics

Other diuretics

Other treatments of attacks

Triggers to avoid

Preventative diet

Preventative potassium intake

Perioperative measures

References

  1. Statland JM, Fontaine B, Hanna MG, et al. Review of the diagnosis and treatment of periodic paralysis. Muscle Nerve 2018; 57:522-530.
  2. Meola G, Hanna MG, Fontaine B. Diagnosis and new treatment in muscle channelopathies. JNNP 2009; 80: 360-365. 
  3. Levitt JO. Practical aspects in the management of hypokalemic periodic paralysis. J Transl Med 2008; 6:18.
  4. Sansone VA, Burge J, McDermott MP, et al; Muscle Study Group. Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis. Neurology 2016; 86:1408-1416.

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