HyperCKaemia: systemic causes

Evidence-based neurology checklist on hyperckaemia: systemic causes: Medical causes Obstructive sleep apnoea (OSA) Chronic cardiac disease Hypokalaemia Hyponatraemia Hypothyroidism Hypoparathyroidism Gluten sensitivity (Coeliac disease) Viral infections Legionella infection Drug-induced…

Medical causes

  • Obstructive sleep apnoea (OSA)
  • Chronic cardiac disease
  • Hypokalaemia
  • Hyponatraemia
  • Hypothyroidism
  • Hypoparathyroidism
  • Gluten sensitivity (Coeliac disease)
  • Viral infections
  • Legionella infection

Drug-induced

Physiologic causes

Familial

Traumatic causes

References

  1. De Bleeker JL. How to approach the patient with muscular symptoms in the general neurological practice? Acta Neurol Belg 2005; 105:18-22.
  2. Lingaraju N, Rosenberg H. Unexplained increases in serum creatine kinase levels: its relation to malignant hyperthermia susceptibility. Anesth Analg 1991; 72:702-705.
  3. Kyriakides T, Angelini C, Schefer J, et al. EFNS guidelines on the diagnostic approach to pauci- or asymptomatic hyperCKemia. Eur J Neurol 2010; 17:767-773.
  4. Goldenberg I, Jonas M, Thaler M, Grossman E. Elevated levels of serum creatinine kinase induced by hyponatraemia. Postgrad Med J 1997; 73:511–512.
  5. Barber J, Butler RC, Davie MWJ, Sewry CA. Hypoparathyroidism presenting as myopathy with raised creatine kinase. Rheumatology 2001; 40:1417-1418.
  6. And 5 more. Subscribe to see the full list

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