Haematoma expansion: risk factors

Evidence-based neurology checklist on haematoma expansion: risk factors: Clinical risk factors Early stroke presentation Oral anticoagulant use High international normalised ratio (INR) Systemic inflammation Elevated D-dimer Reduced platelet activity Apolipoprotein ε2 (APOE2) genotype: this also…

Clinical risk factors

  • Early stroke presentation
  • Oral anticoagulant use
  • High international normalised ratio (INR)
  • Systemic inflammation
  • Elevated D-dimer
  • Reduced platelet activity
  • Apolipoprotein ε2 (APOE2) genotype: this also predicts the Spot sign on CTA

Haematoma risk factors

The BAT Score for predicting haematoma expansion

References

  1. Goldstein JN, Greenberg SM. Should anticoagulation be resumed after intracerebral hemorrhage? Cleve Clin J Med 2010; 77:791-799.
  2. Moussouttas M. Challenges and controversies in the medical management of primary and antithrombotic-related intracerebral hemorrhage. Ther Adv Neurol Disord 2012; 5:43-56.
  3. Brouwers HB, Chang Y, Falcone GJ, et al. Predicting hematoma expansion after primary intracerebral hemorrhage. JAMA Neurol 2014; 71:158-164.
  4. Flibotte JJ, Hagan N, O'Donnell J, Greenberg SM, Rosand J. Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage. Neurology 2004; 63:1059-1064.
  5. Brouwers HB, Biffi A, Ayres AM, et al. Apolipoprotein E genotype predicts hematoma expansion in lobar intracerebral hemorrhage. Stroke 2012; 43:1490-1495. 
  6. And 4 more. Subscribe to see the full list

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