Guillain Barre syndrome (GBS): predictors of ventilation

Evidence-based neurology checklist on guillain barre syndrome (gbs): predictors of ventilation: Clinical indications Older age Weak cough Bilateral facial weakness Bulbar dysfunction Neck flexion weakness Generalised severe weakness Cranial nerve involvement Rapidly progressive course Associated…

Clinical indications

  • Older age
  • Weak cough
  • Bilateral facial weakness
  • Bulbar dysfunction
  • Neck flexion weakness
  • Generalised severe weakness
  • Cranial nerve involvement
  • Rapidly progressive course
  • Associated dysautonomia
  • Underlying pulmonary disease
  • Cardiovascular co-morbidities
  • Poor values on scoring scales: EGRIS and MRC sum scores

Laboratory indications

The 20-40-30 rule indication

Acronyms

References

  1. Fish M, Llewelyn G. The Guillain-Barre syndrome. ACNR 2008; 8:10-12.
  2. Walgaard, C, Lingsma, HF, Ruts, L et al. Prediction of respiratory insufficiency in Guillain-Barré syndrome. Ann Neurol 2010; 67:781–787.
  3. Oshima Y, Mitsui T, Yoshino H, et al. Central motor conduction in patients with anti-ganglioside antibody associated neuropathy syndromes and hyperreflexia. JNNP 2002; 73:568-573.
  4. Asbury AK, Cornblath DR. Assessment of current diagnostic criteria for Guillain-Barre syndrome. Ann Neurol 1990; 27(Suppl):S21-S24.
  5. Lawn ND, Fletcher DD, Henderson RD, Wolter TD, Wijdicks EF. Anticipating mechanical ventilation in Guillain-Barre syndrome. Arch Neurol 2001; 58:893-898.

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