Guillain Barre syndrome (GBS): investigations
Evidence-based neurology checklist on guillain barre syndrome (gbs): investigations: Cerebrospinal fluid (CSF) analysis The CFS shows albumino-cytologic dissociation This is a high protein level with a disproportionately lower cell count Higher protein correlates with early severe disease course…
Cerebrospinal fluid (CSF) analysis
- The CFS shows albumino-cytologic dissociation
- This is a high protein level with a disproportionately lower cell count
- Higher protein correlates with early severe disease course
- The cell count is <5 cells/μL in more than 80% of cases
- Cell counts ≥50 cells/μL can be compatible with GBS
Nerve conduction studies (NCS):
Magnetic resonance imaging (MRI)
Other investigations
References
- Gordon PH, Wilbourn AJ. Early electrodiagnostic findings in Guillain-Barre syndrome. Arch Neurol 2001; 58:913-917.
- Al-Hakem H, Doets AY, Stino AM, et al. CSF findings in relation to clinical characteristics, subtype, and disease course in patients with Guillain-Barré syndrome Neurology 2023; 100:e2386-e2397.
- Atanasova D, Ishpekova B, Muradyan N, Novachkova S, Daskalov M. Conduction block- the diagnostic value in the early stage of Guillain-Barre syndrome. Electromyogr Clin Neurophysiol 2004; 44:361-364.
- Derksen A, Ritter C, Athar P, et al. Sural sparing pattern discriminates Guillain-Barré syndrome from its mimics. Muscle Nerve 2014; 50:780-784.
- Umapathi T, Li Z, Verma K, Yuki N. Sural-sparing is seen in axonal as well as demyelinating forms of Guillain-Barré syndrome. Clin Neurophysiol 2015; 126:2376-2380.
- And 3 more. Subscribe to see the full list
