Germ cell tumours: tumour markers and genetics
Evidence-based neurology checklist on germ cell tumours: tumour markers and genetics: Alpha-fetoprotein (AFP) Endodermal sinus tumours Mixed germ cell tumours Immature teratomas Beta human chorionic gonadotrophi (beta hCG) Placental alkaline phosphatase (PLAP) C-KIT Genetic mutations
Alpha-fetoprotein (AFP)
- Endodermal sinus tumours
- Mixed germ cell tumours
- Immature teratomas
Beta human chorionic gonadotrophi (beta hCG)
Placental alkaline phosphatase (PLAP)
C-KIT
Genetic mutations
References
- Echevarría ME, Fangusaro J, Goldman S. Pediatric central nervous system germ cell tumors: a review. Oncologist 2008; 13:690-699.
- Aihara Y, Watanabe S, Amano K, et al. Placental alkaline phosphatase levels in cerebrospinal fluid can have a decisive role in the differential diagnosis of intracranial germ cell tumors. J Neurosurg 2018; doi: 10.3171/2018.3.JNS172520 (Epub ahead of print).
- Kong Z, Wang Y, Dai C, Yao Y, Ma W, Wang Y. Central nervous system germ cell tumors: a review of the literature. J Child Neurol 2018; 33:610-620.
- Dufour C, Guerrini-Rousseau L, Grill J. Central nervous system germ cell tumors: an update. Curr Opin Oncol 2014; 26:622-626.