Functional seizures: clinical features

Evidence-based neurology checklist on functional seizures: clinical features: General features They may arise from apparent sleep but EEG verifies wakefulness They may however also arise from slow wave sleep The onset is gradual with a waxing and waning course There is no tonic phase About 60%…

General features

  • They may arise from apparent sleep but EEG verifies wakefulness
  • They may however also arise from slow wave sleep
  • The onset is gradual with a waxing and waning course
  • There is no tonic phase
  • About 60% have stereotyped events
  • They are prolonged events usually lasting more than 2 minutes
  • Injury avoidance is characteristic
  • There may be experiential avoidance
  • There is memory recall

Characteristic movements

Panic symptoms

Eye features

Cognitive features

Frequent co-morbidities

Assessment

Synonyms

References

  1. LaFrance WC Jr, Baker GA, Duncan R, Goldstein LH, Reuber M. Minimum requirements for the diagnosis of psychogenic nonepileptic seizures: a staged approach: a report from the International League Against Epilepsy Nonepileptic Seizures Task Force. Epilepsia 2013; 54:2005-2018. 
  2. Mellers JDC. The approach to patients with "non-epileptic seizures". Postgrad Med J 2005; 81:498-504.
  3. Avbersek A, Sisodiya S. Does the primary literature provide support for clinical signs used to distinguish psychogenic nonepileptic seizures from epileptic seizures? JNNP 2010; 81:719-725.
  4. Duncan R. How do you identify and manage convulsive psychogenic nonepileptic seizures presenting acutely to casualty? ACNR 2012; 12:18-20.
  5. Higgins S, Koutroumanidis M. Psychogenic non-epileptic seizures arising almost exclusively from sleep. Seizure 2022; 99:43-47.
  6. And 15 more. Subscribe to see the full list

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