Fibromyalgia

Evidence-based neurology checklist on fibromyalgia: Pathophysiology It may be a neuropathic pain syndrome driven by sympathetic hyperactivity General features Neurological features Psychiatric features Associated pain features Other features Assessment scales Differential diagnosis

Pathophysiology

  • It may be a neuropathic pain syndrome driven by sympathetic hyperactivity

General features

Neurological features

Psychiatric features

Associated pain features

Other features

Assessment scales

Differential diagnosis

References

  1. Wolfe F, Clauw DJ, Fitzcharles M-A, et al. Fibromyalgia criteria and severity scales for clinical and epidemiological studies: a modification of the ACR Preliminary Diagnostic Criteria for Fibromyalgia. J Rheumatol 2011; 38:1113-1122.
  2. Bennett RM, Friend R, Marcus D, et al. Criteria for the diagnosis of fibromyalgia: validation of the modified 2010 preliminary American College of Rheumatology Criteria and the development of alternative criteria. Arthritis Care Res (Hoboken) 2014; 66:1364-1373. 
  3. Martinez-Lavin M. Fibromyalgia: when distress becomes (un)sympathetic pain. Pain Res Treat 2012; 2012:981565.
  4. Evdokimov D, Frank J, Klitsch A, et al. Reduction of skin innervation is associated with a severe fibromyalgia phenotype. Ann Neurol 2019; 86:504-516. 
  5. Segura-Jiménez V, Aparicio VA, Álvarez-Gallardo IC, et al. Validation of the modified 2010 American College of Rheumatology diagnostic criteria for fibromyalgia in a Spanish population. Rheumatology (Oxford) 2014; 53:1803-1811.
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