Fatal familial insomnia (FFI): clinical features
Evidence-based neurology checklist on fatal familial insomnia (ffi): clinical features: Onset features The onset age is between 20-72 years The average onset age is 49 years Cognitive features Psychiatric features Autonomic features Movement disorders Ophthalmological features Bulbar features…
Onset features
- The onset age is between 20-72 years
- The average onset age is 49 years
Cognitive features
Psychiatric features
Autonomic features
Movement disorders
Ophthalmological features
Bulbar features
Other neurological features
Differential diagnosis
References
- Gambetti P, Kong Q, Zou W, Parchi P, Chen SG. Sporadic and familial CJD: classification and characterisation. Br Med Bull 2003; 66:213-239.
- Krasnianski A, Bartl M, Juan PJS, et al. Fatal familial insomnia: clinical features and early identification. Ann Neurol 2008; 63:658-661.
- Brown K, Mastrianni JA. The prion diseases. J Geriatr Psychiatry Neurol 2010; 23:277-298.
- Wu LY, Zhan SQ, Huang ZY, et al. Expert consensus on clinical diagnostic criteria for fatal familial insomnia. Chin Med J (Engl) 2018; 131:1613-1617.
- Yang TW, Park B, Kim KT, et al. Fatal familial insomnia presenting with agrypnia excitata and very low atonia index level: a case report and literature review. Medicine (Baltimore) 2018; 97:e0646.
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