Eslicarbazepine: clinical use

Evidence-based neurology checklist on eslicarbazepine: clinical use: Mode of action Eslicarbazepine is a third generation dibenzazepine It blocks voltage-gated sodium channels (VGSC) Dosing Indications Systemic side effects Neurological side effects Drugs whose blood levels are reduced by…

Mode of action

  • Eslicarbazepine is a third generation dibenzazepine
  • It blocks voltage-gated sodium channels (VGSC)

Dosing

Indications

Systemic side effects

Neurological side effects

Drugs whose blood levels are reduced by Esclicarbazepine

Drugs which reduce Esclicarbazepine blood levels

References

  1. Rocamora R. A review of the efficacy and safety of eslicarbazepine acetate in the management of partial-onset seizures. Ther Adv Neurol Disord 2015; 8:178-186. 
  2. Shirley M, Dhillon S. Eslicarbazepine Acetate Monotherapy: A Review in Partial-Onset Seizures. Drugs 2016; 76:707-717. 
  3. Tambucci R, Basti C, Maresca M, Coppola G, Verrotti A. Update on the role of eslicarbazepine acetate in the treatment of partial-onset epilepsy. Neuropsychiatr Dis Treat 2016; 12:1251-1260. 
  4. Chaves J, Breia P, Pimentel J, et al. Eslicarbazepine acetate as adjunctive therapy in clinical practice: ESLADOBA study. Acta Neurol Scand 2017; 264:421-431.
  5. Galiana GL, Gauthier AC, Mattson RH. Eslicarbazepine acetate: a new improvement on a classic drug family for the treatment of partial-onset seizures. Drugs R D 2017; 17:329-339. 
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