Epilepsy prognosis

Evidence-based neurology checklist on epilepsy prognosis: Indicators of good epilepsy prognosis New onset epilepsy Idiopathic and cryptogenic epilepsy Low seizure frequency before treatment (seizure density) Absence of neurological deficits Early commencement of antiepileptic drugs (AEDs) after…

Indicators of good epilepsy prognosis

  • New onset epilepsy
  • Idiopathic and cryptogenic epilepsy
  • Low seizure frequency before treatment (seizure density)
  • Absence of neurological deficits
  • Early commencement of antiepileptic drugs (AEDs) after first seizure
  • Good early treatment response

Indicators of poor epilepsy prognosis

Mortality indicators

References

  1. Kwan P, Sander JW. The natural history of epilepsy: an epidemiological view. JNNP 2004; 75:1376-1381.
  2. Shorvon SD, Goodridge DM. Longitudinal cohort studies of the prognosis of epilepsy: contribution the National General Practice Study of Epilepsy and other studies. Brain 2013; 136:3497-3510. 
  3. Sillanpää M, Schmidt D. Long-term outcome of medically treated epilepsy. Seizure 2017; 44:211-216.
  4. Ménétré E, Stefano PD, Megevand P, et al. Antiseizure medication ≤48 hours portends better prognosis in new-onset epilepsy. Eur J Neurol 2024; 31:e16107. 
  5. Camfield P, Camfield C, Arts WF, Brouwer OF, Arzimanoglou A. The outcome of childhood epilepsy: what improvements are needed? Epileptic Disord 2013; 15:101-104.
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