Edoxaban

Evidence-based neurology checklist on edoxaban: Pharmacology Edoxaban is a factor Xa inhibitor Dose Risk factors for bleeding Treatment of bleeding

Pharmacology

  • Edoxaban is a factor Xa inhibitor

Dose

Risk factors for bleeding

Treatment of bleeding

References

  1. Hart RG, Diener HC, Yang S, et al. Intracranial hemorrhage in atrial fibrillation patients during anticoagulation with warfarin or dabigatran: the RE-LY trial. Stroke 2012; 43:1511-1517.
  2. Kreuzer J. Update on anti-coagulation in atrial fibrillation. Q J Med 2011; 104:747-760.
  3. Cervantes CE, Merino JL, Barrios V. Edoxaban for the prevention of stroke in patients with atrial fibrillation. Expert Rev Cardiovasc Ther 2019; 17:319-330. 
  4. Okumura K, Akao M, Yoshida T, et al. Low-dose edoxaban in very elderly patients with atrial fibrillation. N Engl J Med 2020 (Online ahead of print).
  5. Mikami T, Hirabayashi K, Okawa K, et al. Laboratory test predictors for major bleeding in elderly (≥80 years) patients with nonvalvular atrial fibrillation treated with edoxaban 15 mg: sub-analysis of the ELDERCARE-AF Trial. J Am Heart Assoc 2022; 11:e024970.
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