Dravet syndrome: treatment
Evidence-based neurology checklist on dravet syndrome: treatment: Effective anti-epileptic drugs (AEDs) Valproate Clonazepam Stiripentol Possibly effective anti-epileptic drugs (AEDs) Contraindicated anti-epileptic drugs Seizure triggers to avoid Other interventions Investigational treatments
Effective anti-epileptic drugs (AEDs)
- Valproate
- Clonazepam
- Stiripentol
Possibly effective anti-epileptic drugs (AEDs)
Contraindicated anti-epileptic drugs
Seizure triggers to avoid
Other interventions
Investigational treatments
References
- van Dam VS, Korff CM. Dravet syndrome: an update. Schweiz Arch Neurol Psychiatr 2013; 164:153-157.
- Wilmshurst JM, Gaillard WD, Vinayan KP, et al. Summary of recommendations for the management of infantile seizures: Task Force Report for the ILAE Commission of Pediatrics. Epilepsia 2015; 56:1185-1197.
- Wirrell EC, Laux L, Franz DN, et al. Stiripentol in Dravet syndrome: results of a retrospective U.S. study. Epilepsia 2013; 54:1595-1604.
- Myers KA, Lightfoot P, Patil SG, Cross JH, Scheffer IE. Stiripentol efficacy and safety in Dravet syndrome: a 12-year observational study. Dev Med Child Neurol 2018; doi: 10.1111/dmcn.13704 (Epub ahead of print).
- Schoonjans A, Paelinck BP, Marchau F, et al. Low-dose fenfluramine significantly reduces seizure frequency in Dravet syndrome: a prospective study of a new cohort of patients. Eur J Neurol 2017; 24:309-314.
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