Doose syndrome: treatment
Evidence-based neurology checklist on doose syndrome: treatment: Anti-epileptic drugs (AEDs) Ethosuximide: especially if absences predominate Valproate Lamotrigine: for generalised seizures Levetiracetam: this is possibly effective Zonisamide: this is possibly effective AEDs to avoid Diet…
Anti-epileptic drugs (AEDs)
- Ethosuximide: especially if absences predominate
- Valproate
- Lamotrigine: for generalised seizures
- Levetiracetam: this is possibly effective
- Zonisamide: this is possibly effective
AEDs to avoid
Diet therapies
Synonym
References
- Kelley SA, Kossoff EH. Doose syndrome (myoclonic-astatic epilepsy): 40 years of progress. Dev Med Child Neurol 2010; 52:988-993.
- Kural Z, Ozer AF. Epileptic encephalopathies in adults and childhood. Epilepsy Res Treat 2012; 2012:205131.
- Oguni H, Fukuyama Y, Tanaka T, et al. Myoclonic-astatic epilepsy of early childhood-clinical and EEG analysis of myoclonic-astatic seizures, and discussions on the nosology of the syndrome. Brain Dev 2001; 23:757-764.
- Palmer S, Towne MC, Pearl PL, et al. SLC6A1 mutation and ketogenic diet in epilepsy with myoclonic-atonic seizures. Pediatr Neurol 2016; 64:77-79.
- Wiemer-Kruel A, Haberlandt E, Hartmann H, Wohlrab G, Bast T. Modified Atkins diet is an effective treatment for children with Doose syndrome. Epilepsia 2017; 58:657-662.
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