Dialysis disequilibrium syndrome (DDS): clinical features

Evidence-based neurology checklist on dialysis disequilibrium syndrome (dds): clinical features: Pathological features This develops at the start of haemodialysis It results from rapid removal of urea This causes an osmotic shift of fluid into the brain parenchyma It may occur during dialysis or…

Pathological features

  • This develops at the start of haemodialysis
  • It results from rapid removal of urea
  • This causes an osmotic shift of fluid into the brain parenchyma
  • It may occur during dialysis or be delayed up to 24 hours post- dialysis
  • It lasts a few hours

Risk factors

Clinical features

Differential diagnosis

References

  1. Sprague SM, Corwin HL, Tanner CM, Wilson RS, Green BJ, Goetz CG. Relationship of aluminum to neurocognitive dysfunction in chronic dialysis patients. Arch Intern Med 1988; 148:2169-2172.
  2. Bellamkonda A, Chowdhury T, Shankar M, Gousy N. Dialysis disequilibrium syndrome: a red flag to check post hemodialysis. Cureus 2022; 14:e24619. 
  3. Chang CH, Hsu KT, Lee Chet al. Leukoencephalopathy associated with dialysis disequilibrium syndrome. Ren Fail 2007; 29:631-634.
  4. Adapa S, Konala VM, Aeddula NR, Gayam V, Naramala S. Dialysis disequilibrium syndrome: rare serious complication of hemodialysis and effective management. Cureus 2019; 11:e5000.
  5. Mistry K. Dialysis disequilibrium syndrome prevention and management. Int J Nephrol Renovasc Dis 2019; 12:69-77.
  6. And 5 more. Subscribe to see the full list

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