Cyclical vomiting syndrome (CVS)
Evidence-based neurology checklist on cyclical vomiting syndrome (cvs): Definition This is a chronic disorder There are sudden episodes of nausea and vomiting The episodes last 1–5 days The frequency is about 9 times a year in children and 14 in adults It may be related to dysfunction in the…
Definition
- This is a chronic disorder
- There are sudden episodes of nausea and vomiting
- The episodes last 1–5 days
- The frequency is about 9 times a year in children and 14 in adults
- It may be related to dysfunction in the insular cortex
Diagnostic criteria
Triggers
Prodromal symptoms
Associated features
Differential diagnosis
Treatment
Features of migraine-associated CVS
Acute treatment of migraine-associated CVS
Preventative treatment of migraine-associated CVS
References
- Hayes WJ, VanGilder D, Berendse J, Lemon MD, Kappes JA. Cyclic vomiting syndrome: diagnostic approach and current management strategies. Clin Exp Gastroenterol 2018; 11:77-84.
- Ellingsen DM, Garcia RG, Lee J, et al. Cyclic vomiting syndrome is characterized by altered functional brain connectivity of the insular cortex: a cross-comparison with migraine and healthy adults. Neurogastroenterol Motil 2017; 29:10.1111/nmo.13004.
- Li BU, Murray RD, Heitlinger LA, Robbins JL, Hayes JR. Is cyclic vomiting syndrome related to migraine? J Pediatr 1999; 134:567-572.
- Ferretti A, Fanfoni C, Vadrucci F, et al. Cyclic vomiting syndrome in pediatric population: characteristics and prophylactic response to cyproheptadine. Minerva Pediatr (Torino) 2024 (Online ahead of print).
- Hayes WJ, Weisensee LA, Kappes JA, Dalton SM, Lemon MD. Onabotulinumtoxin A injections for the treatment of cyclic vomiting syndrome. Pharmacotherapy 2015; 35:e51-e55.
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