Critical illness neuropathy (CIN)

Evidence-based neurology checklist on critical illness neuropathy (cin): Risk factors Sepsis Systemic inflammatory response syndrome (SIRS) Multiorgan failure Severity of illness Duration of intensive therapy unit (ITU) stay Hyperglycaemia Renal failure Hyperosmolality Parenteral nutrition…

Risk factors

  • Sepsis
  • Systemic inflammatory response syndrome (SIRS)
  • Multiorgan failure
  • Severity of illness
  • Duration of intensive therapy unit (ITU) stay
  • Hyperglycaemia
  • Renal failure
  • Hyperosmolality
  • Parenteral nutrition

Pathology

Clinical features

Differential diagnosis

Treatment

Prognosis

References

  1. Latronico N, Bolton CF. Critical illness polyneuropathy and myopathy: a major cause of muscle weakness and paralysis. Lancet Neurol 2011; 10:931-941.
  2. De Letter MACJ, Visser LH, Ang W, van Der Meche FGA, Savelkoul HF. Distinctions between critical illness polyneuropathy and axonal Guillain-Barre syndrome. JNNP 2000; 68:397-398.
  3. Guarneri B, Bertolini G, Latronico N. Long-term outcome in patients with critical illness myopathy or neuropathy: the Italian multicentre CRIMYNE study. JNNP 2008; 79:838-841.
  4. Koch S, Spuler S, Deja M, et al. Critical illness myopathy is frequent: accompanying neuropathy protracts ICU discharge. JNNP 2011; 82:287-293.

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