Corticobasal syndrome (CBS): investigations

Evidence-based neurology checklist on corticobasal syndrome (cbs): investigations: Imaging investigations MRI: asymmetrical perirolandic cortical atrophy DAT scan: this is usually abnormal Amyloid imaging: this may detect AD changes PiB-PET scan: this may detect AD changes FDG-PET scan: this shows…

Imaging investigations

  • MRI: asymmetrical perirolandic cortical atrophy
  • DAT scan: this is usually abnormal
  • Amyloid imaging: this may detect AD changes
  • PiB-PET scan: this may detect AD changes
  • FDG-PET scan: this shows asymmetrical hypometabolism
  • SPECT

Neurophysiological investigations

Cerebrospinal fluid (CSF) analysis

Acronyms

References

  1. Wilson D, Le Heron C, Anderson T. Corticobasal syndrome: a practical guide. Practical Neurol 2021; 21:276-285.
  2. Parmera JB, Rodriguez RD, Studart Neto A, Nitrini R, Brucki SMD. Corticobasal syndrome: a diagnostic conundrum. Dement Neuropsychol 2016; 10:267-275.
  3. Bensaïdane MR, Fortin M-P, Damasse G, et al. Clinical utility of amyloid imaging in a complex case of corticobasal syndrome presenting with psychiatric symptoms. J Neurol Disord 2014; 2:1-4.
  4. Turaga SP, Mridula R, Borgohain R. Cerebral glucose metabolism, clinical, neuropsychological, and radiological profile in patients with corticobasal syndrome. Neurol India 2013; 61:7-11.
  5. Murgai AA, Jog MS. Neurophysiology and neurochemistry of corticobasal syndrome. J Neurol 2018; 265:991-998. 
  6. And 2 more. Subscribe to see the full list

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