Corticobasal degeneration (CBD): differential diagnosis

Evidence-based neurology checklist on corticobasal degeneration (cbd): differential diagnosis: Differential diagnosis Progressive supranuclear palsy (PSP): vertical gaze palsy Multiple system atrophy (MSA): severe autonomic dysfunction Parkinson’s disease (PD): rest tremor and levodopa…

Differential diagnosis

  • Progressive supranuclear palsy (PSP): vertical gaze palsy
  • Multiple system atrophy (MSA): severe autonomic dysfunction
  • Parkinson’s disease (PD): rest tremor and levodopa responsiveness
  • Alzheimer’s disease (AD): early dementia
  • Frontotemporal degeneration (FTD)
  • Cerebrotendinous xanthomatosis (CTX)
  • Gaucher’s disease

References

  1. Mathew R, Bak TH, Hodges JR. Diagnostic criteria for corticobasal syndrome: a comparative study. JNNP 2012; 83:405-410.
  2. Stamelou M, Quinn NP, Bhatia KP. "Atypical" atypical parkinsonism: new genetic conditions presenting with features of progressive supranuclear palsy, corticobasal degeneration, or multiple system atrophy-a diagnostic guide. Mov Disord 2013; 28:1184-1199.

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