Cortical myoclonus

Evidence-based neurology checklist on cortical myoclonus: Pathology The cortex is normal apart from occasional gliosis There is cerebellar atrophy and degeneration: this especially involves the Purkinje cells Causes Causes of multifocal cortical myoclonus Clinical features Triggers (stimulus…

Pathology

  • The cortex is normal apart from occasional gliosis
  • There is cerebellar atrophy and degeneration: this especially involves the Purkinje cells

Causes

Causes of multifocal cortical myoclonus

Clinical features

Triggers (stimulus sensitivity)

Somatosensory evoked potentials (SEPs)

References

  1. Tijssen MA, Thom M, Ellison DW, et al. Cortical myoclonus and cerebellar pathology. Neurology 2000; 54:1350-1356.
  2. Kojovic M, Cordivari C, Bhatia K. Myoclonic disorders: a practical approach for diagnosis and treatment. Ther Adv Neurol Disord 2011; 4:47-62.
  3. Velilla-Alonso G, Martín-Miguel MDC, Massot-Tarrús A. Cortical myoclonus associated with coeliac disease showing a characteristic EEG pattern: A case report. Seizure 2022; 95:81-83.

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