CLIPPERS: treatment

Evidence-based neurology checklist on clippers: treatment: Steroid treatment Steroid responsiveness is not universal Symptoms may relapse on steroid tapering Steroid-sparing immunosuppression: conventional types Steroid-sparing immunosuppression: case reports Acronym

Steroid treatment

  • Steroid responsiveness is not universal
  • Symptoms may relapse on steroid tapering

Steroid-sparing immunosuppression: conventional types

Steroid-sparing immunosuppression: case reports

Acronym

References

  1. Taieb G, Allou T, Labauge P. Therapeutic approaches in CLIPPERS. Curr Treat Options Neurol 2017; 19:17. 
  2. Tobin WO, Guo Y, Krecke KN, et al. Diagnostic criteria for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS). Brain 2017; 140:2415-2425.
  3. Rico M, Villafani J, Tuñón A, Mateos V, Oliva-Nacarino P. IFN beta 1a as glucocorticoids-sparing therapy in a patient with CLIPPERS. Am J Case Rep 2016; 17:47-50.
  4. Cipriani VP, Arndt N, Pytel P, Reder AT, Javed A. Effective treatment of CLIPPERS with long-term use of rituximab. Neurol Neuroimmunol Neuroinflamm 2018; 5:e448.
  5. Rempe T, Becktepe JS, Metz I, et al. A case of CLIPPERS syndrome responsive to tocilizumab. Neurol Neuroimmunol Neuroinflamm 2019; 6:e545.
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