CIDP: investigations

Evidence-based neurology checklist on cidp: investigations: Nerve conduction studies (NCS): features Prolonged distal motor latency Reduced velocities Prolonged F wave latency Temporal dispersion Conduction block Slow motor nerve conduction velocity (mNCV): this is <80% of the lower limit Sensory…

Nerve conduction studies (NCS): features

  • Prolonged distal motor latency
  • Reduced velocities
  • Prolonged F wave latency
  • Temporal dispersion
  • Conduction block
  • Slow motor nerve conduction velocity (mNCV): this is <80% of the lower limit
  • Sensory NCS is not sensitive

Cerebrospinal fluid (CSF) analysis

Nerve ultrasound

Autoantibodies

Other investigations

Emerging investigations

Acronym

References

  1. The French CIDP Group, Vallat JM. Recommendations on diagnostic strategies for chronic inflammatory demyelinating polyradiculopathy. Postgrad Med J 2008; 84:378-381.
  2. The French CIDP Group. Recommendations on diagnostic strategies for chronic inflammatory demyelinating polyradiculopathy. JNNP 2008; 79:115-118.
  3. Vallat JM, Sommer C, Magy L. Chronic inflammatory demyelinating polyradiculoneuropathy: diagnostic and therapeutic challenges for a treatable condition. Lancet Neurol 2010; 9:402-412.
  4. Capodivento G, De Michelis C, Carpo M, et al. CSF sphingomyelin: a new biomarker of demyelination in the diagnosis and management of CIDP and GBS. JNNP 2020 (Online ahead of print).
  5. Grimm A, Schubert V, Axer H, Ziemann U. Giant nerves in chronic inflammatory polyradiculoneuropathy. Muscle Nerve 2017; 55:285-289. 
  6. And 13 more. Subscribe to see the full list

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