Chiasmal syndrome: causes

Evidence-based neurology checklist on chiasmal syndrome: causes: Tumours Pituitary adenoma: this is the most frequent cause Posterior fossa tumours Meningioma Astrocytoma Oligodendroglioma Nasopharyngeal carcinoma Glioblastoma multiforme Optic chiasma de novo glioma Hypophyseal tumours Uveal…

Tumours

  • Pituitary adenoma: this is the most frequent cause
  • Posterior fossa tumours
  • Meningioma
  • Astrocytoma
  • Oligodendroglioma
  • Nasopharyngeal carcinoma
  • Glioblastoma multiforme
  • Optic chiasma de novo glioma
  • Hypophyseal tumours
  • Uveal melanoma chiasmal extension
  • Lymphoma
  • Ganglioglioma
  • Primary chiasmal germinoma

Other structural causes

Traumatic optic chiasmopathy

Vascular

Inflammatory

Infectious

Hereditary optic neuropathies

Drug-induced

Iatrogenic

Other causes

References

  1. Mejico LJ, Miller NR, Dong LM. Clinical features associated with lesions other than pituitary adenoma in patients with an optic chiasmal syndrome. Am J Ophthalmol 2004; 137:908-913. 
  2. Astorga-Carballo A, Serna-Ojeda JC, Camargo-Suarez MF. Chiasmal syndrome: clinical characteristics in patients attending an ophthalmological center. Saudi J Ophthalmol 2017; 31:229-233. 
  3. Wadud S.A., Ahmed S., Choudhury N., Chowdhury D. Evaluation of ophthalmic manifestations in patients with intracranial tumours. Mymensingh Med J; 2014; 23:268-271.
  4. Karimaghaei C, Pakravan M, Charoenkijkajorn C, Lee VA, Lee AG. Visual loss as the presenting manifestation of leptomeningeal spread of glioblastoma multiforme to the optic chiasm. J Neuroophthalmol 2022 (Online ahead of print).
  5. Dinh TT, Wang YY, Rosenfeld JV, Cherny M. Glioblastoma of the optic chiasm. J Clin Neurosci 2007; 14:502-505.
  6. And 44 more. Subscribe to see the full list

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