Cerebral vein thrombosis (CVT): haematological risk factors

Evidence-based neurology checklist on cerebral vein thrombosis (cvt): haematological risk factors: Thrombophilia Antithrombin III deficiency Protein C/S deficiency Factor V Leiden mutation Prothrombin gene mutation Antiphospholipid antibodies Hyperhomocysteinemia Antiphospholipid/anticardiolipin…

Thrombophilia

  • Antithrombin III deficiency
  • Protein C/S deficiency
  • Factor V Leiden mutation
  • Prothrombin gene mutation
  • Antiphospholipid antibodies
  • Hyperhomocysteinemia
  • Antiphospholipid/anticardiolipin antibodies
  • Resistance to activated protein C
  • Factor II G20210A mutation
  • Elevated factor VIII (FVIII) level

Blood disorders

Other haematological disorders

Synonym

References

  1. Piazza G. Cerebral venous thrombosis. Circulation 2012; 125:1704-1709.
  2. Saposnik G, Berinagarrementeria F, Brown Jr RD, et al. Diagnosis and management of vertebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2011; 42:1158-1192.
  3. Vecht L, Zuurbier SM, Meijers JCM, Coutinho JM. Elevated factor VIII increases the risk of cerebral venous thrombosis: a case-control study. J Neurol 2018; 265:1612-1617.
  4. Anadure RK, Nagaraja D, Christopher R. Plasma factor VIII in non-puerperal cerebral venous thrombosis: a prospective case-control study. J Neurol Sci 2014; 339:140-143.
  5. Farias-Moeller R, Siddiqui S, Orr M, Mondok L. Too much of a good thing? Cerebral sinovenous thrombosis due to excessive milk intake associated with anemia. J Child Neurol 2020; 35:585-590.
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