Cerebral cavernous malformations (cavernomas): MRI features
Evidence-based neurology checklist on cerebral cavernous malformations (cavernomas): mri features: Typical MRI features Cavernomas typically demonstrate a popcorn appearance on MRI They are circumscribed lobulated areas They have a reticulated heterogeneous signal intensity core There is blooming…
Typical MRI features
- Cavernomas typically demonstrate a popcorn appearance on MRI
- They are circumscribed lobulated areas
- They have a reticulated heterogeneous signal intensity core
- There is blooming on gradient recalled echo/SWI and DWI sequences
- There is mixed signal on DWI sequences
- There are associated venous malformations in 30% of lesions
- The venous drainage may be solitary or multiple
- There are large outflow vessels
- There are white matter hyperintensities
Atypical MRI features
MRI locations
MRI differentials
Zabramski classification for cerebral cavernomas
Scoring systems for spinal cavernomas
Monitoring protocol
Recommended MRI sequences
MRI diagnostic criteria
References
- Kuroedov D, Cunha B, Pamplona J, Castillo M, Ramalho J. Cerebral cavernous malformations: typical and atypical imaging characteristics. J Neuroimaging 2022 (Online ahead of print).
- Dammann P, Wrede KH, Maderwald S, et al. The venous angioarchitecture of sporadic cerebral cavernous malformations: a susceptibility weighted imaging study at 7 T MRI. JNNP 2013; 84:194-200.
- Golden MJ, Morrison LA, Kim H, Hart BL. Increased number of white matter lesions in patients with familial cerebral cavernous malformations. Am J Neuroradiol 2015; 36:899-903.
- Strickland CD, Eberhardt SC, Bartlett MR, et al. Familial cerebral cavernous malformations are associated with adrenal calcifications on CT scans: an imaging biomarker for a hereditary cerebrovascular condition. Radiology 2017; 284:443-450.
- Sun I, Pamir MN. Spinal cavernomas: outcome of surgically treated 10 patients. Front Neurol 2017; 8:672.
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