Cerebral aneurysms: non-aneurysm related risk factors for rupture

Evidence-based neurology checklist on cerebral aneurysms: non-aneurysm related risk factors for rupture: Patient-related risk factors Older age Female gender Non-Caucasian ethnicity Low body weight Within 5 years of aneurysm formation History of previous subarachnoid haemorrhage (SAH) Change in…

Patient-related risk factors

  • Older age
  • Female gender
  • Non-Caucasian ethnicity
  • Low body weight
  • Within 5 years of aneurysm formation
  • History of previous subarachnoid haemorrhage (SAH)
  • Change in character of headaches in the preceding 3 months
  • Occupational physical activity

Medical co-morbidities

Recreational risk factors

Uncertain risk: medications

Possible protective factors against rupture

References

  1. Clarke M. Systematic review of reviews of risk factors for intracranial aneurysms. Neuroradiology 2008; 50:653-664.
  2. Thompson BG, Brown RD Jr, Amin-Hanjani S, et al. American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, and Council on Epidemiology and Prevention; American Heart Association; American Stroke Association. Guidelines for the management of patients with unruptured intracranial aneurysms: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2015; 46:2368-2400. 
  3. Juvela S, Poussa K, Lehto H, Porras M. Natural history of unruptured intracranial aneurysms: a long-term follow-up study. Stroke 2013; 44:2414-2421.
  4. Ishibashi T, Murayama Y, Urashima M, Saguchi T, Ebara M, Arakawa H, Irie K, Takao H, Abe T. Unruptured intracranial aneurysms: incidence of rupture and risk factors. Stroke 2009; 40:313-316.
  5. Mitchell P, Gholkar A, Vindlacheruvu RR, Mendelow AD. Unruptured intracranial aneurysms: benign curiosity or ticking bomb? Lancet Neurol 2004; 3:85-92.
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