Cerebral amyloid angiopathy (CAA): investigations

Evidence-based neurology checklist on cerebral amyloid angiopathy (caa): investigations: Genetic testing If familial and age <50 years Magnetic resonance imaging (MRI) Amyloid biomarkers: A beta and tau CT or MR angiography Pathology

Genetic testing

  • If familial and age <50 years

Magnetic resonance imaging (MRI)

Amyloid biomarkers: A beta and tau

CT or MR angiography

Pathology

References

  1. Cordonnier C, Klijn C, Smith EE, et al. Diagnosis and management of cerebral amyloid angiopathy: a scientific statement from the International CAA Association and the World Stroke Organization. Int J Stroke 2025; 20:949-967.
  2. Mendonça MD, Caetano A, Pinto M, Cruz e Silva V, Viana-Baptista M. Stroke-like episodes heralding a reversible encephalopathy: microbleeds as the key to the diagnosis of cerebral amyloid angiopathy-related inflammation-a case report and literature review. J Stroke Cerebrovasc Dis 2015; 24:e245-250.
  3. Rannikmae K, Samarasekera N, Martinez-Gonzalez NA, Al-Shahi Salman R, Sudlow CLM. Genetics of cerebral amyloid angiopathy: systemic review and meta-analysis. JNNP 2013; 84:901-908.

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