Brain tumours: chemotherapy
Evidence-based neurology checklist on brain tumours: chemotherapy: Temozolomide This is an alkylating agent It improves survival when combined with Valproate Valproate is therefore the antiepileptic drug (AED) of choice Other alkylating agents Bevacizumab Everolimus Steroids Immune checkpoint…
Temozolomide
- This is an alkylating agent
- It improves survival when combined with Valproate
- Valproate is therefore the antiepileptic drug (AED) of choice
Other alkylating agents
Bevacizumab
Everolimus
Steroids
Immune checkpoint inhibitors: types
Investigational immunotherapies
References
- Grant R. Overview: brain tumour diagnosis and management/Royal College of Physicians guidelines. JNNP 2004; 75:(Suppl II):ii18-ii23.
- Laquintana V, Trapani A, Denora N, Wang F, Gallo JM, Trapani G. New strategies to deliver anticancer drugs to brain tumors. Expert Opin Drug Deliv 2009; 6:1017-1032.
- Armand JP, Ribrag V, Harrousseau JL, Abrey L. Reappraisal of the use of procarbazine in the treatment of lymphomas and brain tumors. Ther Clin Risk Manag 2007; 3:213-224.
- Ansstas G, Tran DD. Treatment with tumor-treating fields therapy and pulse dose bevacizumab in patients with bevacizumab-refractory recurrent glioblastoma: a case series. Case Rep Neurol 2016; 8:1-9.
- Franz DN, Belousova E, Sparagana S, et al. Everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: 2-year open-label extension of the randomised EXIST-1 study. Lancet Oncol 2014; 15:1513-1520.
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