Brain tumour related epilepsy (BTRE): treatment

Evidence-based neurology checklist on brain tumour related epilepsy (btre): treatment: First-line antiepileptic drugs (AEDs) Valproate Lamotrigine Topiramate Lacosamide Levetiracetam Zonisamide Add-on antiepileptic drugs (AEDs) Precautions: drug treatments to avoid Precautions: contraindications…

First-line antiepileptic drugs (AEDs)

  • Valproate
  • Lamotrigine
  • Topiramate
  • Lacosamide
  • Levetiracetam
  • Zonisamide

Add-on antiepileptic drugs (AEDs)

Precautions: drug treatments to avoid

Precautions: contraindications to antiepileptic drug withdrawal

Surgery: considerations

Surgery: approaches

Treatment of refractory low grade tumour-related seizures

References

  1. van Breemen MS, Wilms EB, Vecht CJ. Epilepsy in patients with brain tumours: epidemiology, mechanisms, and management. Lancet Neurol 2007; 6:421-430. 
  2. Rudà R, Bello L, Duffau H, Soffietti R. Seizures in low-grade gliomas: natural history, pathogenesis, and outcome after treatments. Neuro Oncol 2012; 14(Suppl 4):iv55-iv64. 
  3. Seidel S, Wehner T, Miller D, Wellmer J, Schlegel U, Grönheit W. Brain tumor related epilepsy: pathophysiological approaches and rational management of antiseizure medication. Neurol Res Pract 2022; 4:45.
  4. Hauff NS, Storstein A. Seizure management and prophylaxis considerations in patients with brain tumors. Curr Oncol Rep 2023; 25:787-792.
  5. Klinger NV, Shah AK, Mittal S. Management of brain tumor-related epilepsy. Neurol India 2017; 65(Supplement):S60-S70. 
  6. And 5 more. Subscribe to see the full list

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