Brain metastases: treatment
Evidence-based neurology checklist on brain metastases: treatment: Surgery ± external beam radiation This is usually indicated for single metastases It may be done for 2-3 metastases if the systemic disease is well-controlled Stereotactic radiosurgery Whole brain radiotherapy (WBR) Chemotherapy…
Surgery ± external beam radiation
- This is usually indicated for single metastases
- It may be done for 2-3 metastases if the systemic disease is well-controlled
Stereotactic radiosurgery
Whole brain radiotherapy (WBR)
Chemotherapy
Dexamethasone
Antiepileptic drugs (AEDs)
Good prognostic factors
References
- Soffietti R, Cornu P, Delattre JY, et al. EFNS guidelines on diagnosis and treatment of brain metastases: report of an EFNS Task Force. Eur J Neurol 2006; 13:674-681.
- Pavel M, Grossman A, Arnold R, et al. ENETS consensus guidelines for the management of brain, cardiac and ovarian metastases from neuroendocrine tumours. Neuroendocrinology 2010; 91:326-332.
- Mikkelsen T, Paleologos NA, Robinson PD, et al. The role of prophylactic anticonvulsants in the management of brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 2010; 96:97-102.
- Ryken TC, McDrrmott M, Robinson PD, et al. The role of steroids in the management of brain metastases: a systematic review and evidence-based clinical practice guideline. J Neurooncol 2010; 96:103-114.
