Brain biopsy: indications and process
Evidence-based neurology checklist on brain biopsy: indications and process: Indications for brain biopsy Central nervous system disease in immunosuppressed patients Rapidly progressive dementia Confirmation of dementia type Suspected Creutzfeldt Jakob disease (CJD) Suspected toxoplasmosis in HIV…
Indications for brain biopsy
- Central nervous system disease in immunosuppressed patients
- Rapidly progressive dementia
- Confirmation of dementia type
- Suspected Creutzfeldt Jakob disease (CJD)
- Suspected toxoplasmosis in HIV
- Cerebral vasculitis
- Atypical demyelination e.g. tumefactive
- Uncertain infection
- Uncertain malignancy
Procedural checklist
Evaluative approach
References
- Gilkes CE, Love S, Hardie RJ, Edwards RJ, Scolding NJ, Rice CM. Brain biopsy in benign neurological disease. J Neurol 2012; 259:995-1000.
- Lee AM, Bai HX, Zou Y, et al. Safety and diagnostic value of brain biopsy in HIV patients: a case series and meta-analysis of 1209 patients. JNNP 2016; 87:722-733.
- Schott JM, Reiniger L, Thom M, et al. Brain biopsy in dementia: clinical indications and diagnostic approach. Acta Neuropathol 2010; 220:327-341.
- Warren JD, Schott JM, Fox NC, et al. Brain biopsy in dementia. Brain 2005; 128:2016-2025.
