Benign essential blepharospasm (BEB)

Evidence-based neurology checklist on benign essential blepharospasm (beb): Risk factors Older age Females Sun exposure Coffee intake Family history of dystonia or postural tremor Non-smoking History of dry eyes Head trauma Dental procedures Genetic mutations: CIZ1, GNAL, SYNE1, REEP4, TOR2A Main…

Risk factors

  • Older age
  • Females
  • Sun exposure
  • Coffee intake
  • Family history of dystonia or postural tremor
  • Non-smoking
  • History of dry eyes
  • Head trauma
  • Dental procedures
  • Genetic mutations: CIZ1, GNAL, SYNE1, REEP4, TOR2A 

Main clinical features

Associated clinical features

Provoking factors

Possible associated disorders

Differential diagnosis (secondary blepharospasm)

Predictors of spread

Treatment

References

  1. Hallett M, Evinger C, Jankovic J, et al. Update on blepharospasm: report from the BEBRF International Workshop. Neurology 2008; 71:1275-1282.
  2. Schwingenschuh,P, Katschnig P, Edwards MJ, et al. The blink reflex recovery cycle differs between essential and presumed psychogenic blepharospasm. Neurology 2011; 76:610-614.
  3. Hallett M. Blepharospasm: recent advances. Neurology 2002; 59:1306-1312.
  4. Molloy A, Williams L, Kimmich O, et al. Sun exposure is an environmental factor for the development of blepharospasm. JNNP 2016; 87:420-424. 
  5. Defazio G, Hallett M, Jinnah HA, Berardelli A. Development and validation of a clinical guideline for diagnosing blepharospasm. Neurology 2013; 81:236-240.
  6. And 7 more. Subscribe to see the full list

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