Anti-MUSK myasthenia gravis (MG): investigations

Evidence-based neurology checklist on anti-musk myasthenia gravis (mg): investigations: Electromyogram (EMG) This shows facial muscle abnormalities in about 75% of cases Single-fiber EMG is often normal The EMG features may mimic inflammatory myopathy There may be myotonic discharges Chest CT

Electromyogram (EMG)

  • This shows facial muscle abnormalities in about 75% of cases
  • Single-fiber EMG is often normal
  • The EMG features may mimic inflammatory myopathy
  • There may be myotonic discharges

Chest CT

References

  1. Wolfe GI, Oh SJ. Clinical phenotype of muscle-specific tyrosine kinase-antibody-positive myasthenia gravis. Ann N Y Acad Sci 2008; 1132:71-75.
  2. Takahashi H, Kawaguchi N, Ito N, Takamichi H, Kuwabara S. Is tongue atrophy reversible in anti-MUSK myasthenia gravis? Six year observation. JNNP 2010; 81:701-702.
  3. Sieb JP. Myasthenia gravis: an update for the clinician. Clin Exp Immunol 2014; 175:408-418.
  4. Skolka M, Lamb CJ, Rubin DI, Klein CJ, Laughlin RS. Electrodiagnostic characteristics suggestive of muscle-specific kinase myasthenia gravis. Neurol Clin Pract 2022; 12:211-217.
  5. Skolka M, Lamb CJ, Rubin DI, Klein CJ, Laughlin RS. Electrodiagnostic characteristics suggestive of muscle-specific kinase myasthenia gravis. Neurol Clin Pract 2022; 12:211-217.

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