Anti-MOG antibody disease (MOGAD): CSF features
Evidence-based neurology checklist on anti-mog antibody disease (mogad): csf features: Anti MOG antibody Anti MOG antibody is less frequently detected in CSF than in serum It may be positive in CSF and negative in serum Positive CSF and MOG antibodies predict severer disease and poorer outcome…
Anti MOG antibody
- Anti MOG antibody is less frequently detected in CSF than in serum
- It may be positive in CSF and negative in serum
- Positive CSF and MOG antibodies predict severer disease and poorer outcome
- Positive CSF anti-MOG is also seen with NMO and ADEM
Other CSF features
Synonyms
References
- Jarius S, Ruprecht K, Kleiter I, et al; in cooperation with the Neuromyelitis Optica Study Group (NEMOS). MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome. J Neuroinflammation 2016; 13:280.
- Jarius S, Kleiter I, Ruprecht K, et al; in cooperation with the Neuromyelitis Optica Study Group (NEMOS). MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 3: Brainstem involvement - frequency, presentation and outcome. J Neuroinflammation 2016; 13:281.
- Aoe S, Kume K, Takata T, et al. Clinical significance of assaying anti-MOG antibody in cerebrospinal fluid in MOG-antibody-associated diseases: a case report. Mult Scler Relat Disord 2019; 28:165-166.
- Mariotto S, Gajofatto A, Batzu L, et al. Relevance of antibodies to myelin oligodendrocyte glycoprotein in CSF of seronegative cases. Neurology 2019; 93:e1867-e1872.
- Carta S, Cobo Calvo Á, Armangué T, et al. Significance of myelin oligodendrocyte glycoprotein antibodies in CSF: a retrospective multicenter study. Neurology 2023; 100:e1095-e1108.
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