Anti Ma2 antibody paraneoplastic syndrome: clinical features

Evidence-based neurology checklist on anti ma2 antibody paraneoplastic syndrome: clinical features: Central phenotypes Limbic encephalitis Diancephalic epilepsy Brainstem encephalitis Subacute cerebellar degeneration (SCD) Myeloradiculopathy Progressive spastic paraparesis Peripheral phenotypes…

Central phenotypes

  • Limbic encephalitis
  • Diancephalic epilepsy
  • Brainstem encephalitis
  • Subacute cerebellar degeneration (SCD)
  • Myeloradiculopathy
  • Progressive spastic paraparesis

Peripheral phenotypes

Encephalitis

Eye movement disorders

Movement disorders

Sleep disorders

Psychiatric disorders

Other features

Differential diagnosis

References

  1. Dalmau J, Graus F, Villarejo A, et al. Clinical analysis of anti-Ma2-associated encephalitis. Brain 2004; 127:1831-1844.
  2. Kraker J. Treatment of anti-Ma2/Ta paraneoplastic syndrome. Curr Treat Options Neurol 2009; 11:46-51.
  3. Rosenfeld MR, Dalmau J. Update on paraneoplastic neurologic disorders. Oncologist 2010; 15:603-617.
  4. Murphy SM, Khan U, Alifrangis C, et al. Anti Ma2-associated myeloradiculopathy: expanding the phenotype of anti-Ma2 associated paraneoplastic syndromes. JNNP 2012; 83:232-233.
  5. Piccolo G, Tavazzi E, Jarius S, et al. Anti-Ma2/Ta antibodies in a woman with primary lateral sclerosis-like phenotype and Sjögren syndrome. Neurol Sci 2011; 32:915-917.
  6. And 26 more. Subscribe to see the full list

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