Anti DPPX autoimmune encephalitis: systemic features

Evidence-based neurology checklist on anti dppx autoimmune encephalitis: systemic features: Gastrointestinal prodrome Loss of appetite Watery diarrhoea Gastroparesis Abdominal pain Constipation Xerostomia Other systemic features Association with B cell cancers

Gastrointestinal prodrome

  • Loss of appetite
  • Watery diarrhoea
  • Gastroparesis
  • Abdominal pain
  • Constipation
  • Xerostomia

Other systemic features

Association with B cell cancers

References

  1. Doherty L, Gold D, Solnes L, Probasco J, Venkatesan A. Anti-DPPX encephalitis: prominent nystagmus reflected by extraocular muscle FDG-PET avidity. Neurol Neuroimmunol Neuroinflamm 2017; 4:e361. 
  2. Hara M, Ariño H, Petit-Pedrol M, et al. DPPX antibody-associated encephalitis: Main syndrome and antibody effects. Neurology 2017; 88:1340-1348. 
  3. Tobin WO, Lennon VA, Komorowski L, et al. DPPX potassium channel antibody: frequency, clinical accompaniments, and outcomes in 20 patients. Neurology 2014; 83:1797-1803. 
  4. Martinez Sosa S, Webb LM, Thomsen A, et al. Pearls & Oy-sters: DPPX antibody-associated encephalitis in a patient with diarrhea, tremor, ocular flutter, and cognitive-psychiatric changes. Neurology 2026; 107:e218522.
  5. Stokin GB, Popović M, Gelpi E, Kogoj A, Dalmau J, Graus F. Neuropathologic features of anti-dipeptidyl-peptidase-like protein-6 antibody encephalitis. Neurology 2015; 84:430-432. 
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