Anti CV2/CRMP5 antibody paraneoplastic syndrome: differential diagnosis

Evidence-based neurology checklist on anti cv2/crmp5 antibody paraneoplastic syndrome: differential diagnosis: Differentials of limbic encephalitis Gliomas Herpes virus encephalitis Status epilepticus Anti LGI1 autoimmune encephalitis Differentials of cerebellar ataxia Differentials of chorea…

Differentials of limbic encephalitis

  • Gliomas
  • Herpes virus encephalitis
  • Status epilepticus
  • Anti LGI1 autoimmune encephalitis

Differentials of cerebellar ataxia

Differentials of chorea

Differentials of myelopathy

Differentials of neuropathy

Acronym

References

  1. Wang S, Hou H, Tang Y, et al. An overview on CV2/CRMP5 antibody-associated paraneoplastic neurological syndromes. Neural Regen Res 2023; 18:2357-2364. 
  2. Cross SA, Salomao DR, Parisi JE, et al. Paraneoplastic autoimmune optic neuritis with retinitis defined by CRMP-5-IgG. Ann Neurol 2003; 54:38-50. 
  3. Jarius S, Wandinger KP, Borowski K, Stoecker W, Wildemann B. Antibodies to CV2/CRMP5 in neuromyelitis optica-like disease: case report and review of the literature. Clin Neurol Neurosurg 2012; 114:331-335.
  4. Dalmau J, Rosenfeld MR. Paraneoplastic syndromes of the CNS. Lancet Neurol 2008; 7:327-340.

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