Amyloid β related angiitis (ABRA)
Evidence-based neurology checklist on amyloid β related angiitis (abra): Pathology This is an inflammatory vasculopathy It is caused by intravascular amyloid deposition It is a complication of cerebral amyloid angiopathy (CAA) It affects younger patients than those with typical CAA Clinical…
Pathology
- This is an inflammatory vasculopathy
- It is caused by intravascular amyloid deposition
- It is a complication of cerebral amyloid angiopathy (CAA)
- It affects younger patients than those with typical CAA
Clinical features
Magnetic resonance imaging (MRI) brain
Other investigations
Treatment
References
- Nguyen JV, Byrne EM, Yuan S, et al. Fulminant amyloid β-related angiitis with herniation and rapid response to tocilizumab: a case report. Neurol Neuroimmunol Neuroinflamm 2026; 13:e200559.
- Danve A, Grafe M, Deodhar A. Amyloid beta-related angiitis - a case report and comprehensive review of literature of 94 cases. Semin Arthritis Rheum 2014; 44:86-92.
- Tanner JA, Richie MB, Cadwell CR, et al. Amyloid-β related angiitis presenting as eosinophilic meningitis: a case report. BMC Neurol 2022; 22:116.
- Nakaya M, Hashimoto H, Usui G, et al. Cerebral amyloid-β-related angiitis without cerebral microbleeds in a patient with subarachnoid hemorrhage. Cardiovasc Pathol 2019; 42:36-40.
