Akinetic mutism

Evidence-based neurology checklist on akinetic mutism: Pathology This is caused by disconnection of frontal-cingulate-limbic subcortical circuits This disrupts the frontal neuronal systems involved with executive functions It is usually associated with anterior cingulate lesions Vascular causes:…

Pathology

  • This is caused by disconnection of frontal-cingulate-limbic subcortical circuits
  • This disrupts the frontal neuronal systems involved with executive functions
  • It is usually associated with anterior cingulate lesions

Vascular causes: stroke

Vascular causes: others

Neoplastic causes

Traumatic causes

Infective causes

Toxic and drug-induced

Other neurological causes

Treatment

References

  1. Mega MS, Cohenour RC. Akinetic mutism: disconnection of frontal-subcortical circuits. Neuropsychiatry Neuropsychol Behav Neurol 1997; 10:254-259.
  2. Németh G, Hegedüs K, Molnár L. Akinetic mutism associated with bicingular lesions: clinicopathological and functional anatomical correlates. Eur Arch Psychiatry Neurol Sci 1988; 237:218-222.
  3. Tengvar C, Johansson B, Sorensen J. Frontal lobe and cingulate cortical metabolic dysfunction in acquired akinetic mutism: a PET study of the interval form of carbon monoxide poisoning. Brain Inj 2004; 18:615-625.
  4. Nagaratnam N, Nagaratnam K, Ng K, Diu P. Akinetic mutism following stroke. J Clin Neurosci 2004; 11:25-30.
  5. Nicolai J, van Putten MJ, Tavy DL. BIPLEDs in akinetic mutism caused by bilateral anterior cerebral artery infarction. Clin Neurophysiol 2001; 112:1726-1728.
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