Agenesis of the corpus callosum: clinical features
Evidence-based neurology checklist on agenesis of the corpus callosum: clinical features: Anatomical associations Malformations of cortical development (MCD): especially grey matter heterotopia Absent or abnormal anterior commissure Absent or abnormal hippocampal commissure Abnormal ventricles…
Anatomical associations
- Malformations of cortical development (MCD): especially grey matter heterotopia
- Absent or abnormal anterior commissure
- Absent or abnormal hippocampal commissure
- Abnormal ventricles
- Probst bundles: longitudinal callosal fascicles
- Inter-hemispheric cysts
- Inter-hemispheric lipomas
Abnormal systems
Clinical associations
References
- Hetts SW, Sherr EH, Vhao S, Gobuty S, Barkovich AJ. Anomalies of the corpus callosum: an MR analysis of the phenotypic spectrum of associated malformations. Am J Roentgenel 2006; 187:1343-1348.
- Barkovich AJ, Simon EM, Walsh C. Callosal agenesis with cyst: a better understanding and new classification. Neurology 2001; 56:220-227.
- dos Santos AC, Midleton SR, Fonseca RL, dos Santos SR, Llerena JC Jr, Vargas FR. Clinical, neuroimaging and cytogenetic findings in 20 patients with corpus callosum dysgenesis. Arq Neuropsiquiatr 2002; 60:382-385.
- Kim YU, Park ES, Jung S, Suh M, Choi HS, Rha DW. Clinical features and associated abnormalities in children and adolescents with corpus callosal anomalies. Ann Rehabil Med 2014; 38:138-143.
- Margari L, Palumbi R, Campa MG, et al. Clinical manifestations in children and adolescents with corpus callosum abnormalities. J Neurol 2016; 263:1939-1945.
