Adrenoleukodystrophy (ALD): systemic features

Evidence-based neurology checklist on adrenoleukodystrophy (ald): systemic features: Addisonian features Bronzed skin pigmentation Scanty hair Gastrointestinal disturbance Fatigue Hypotension Hyponatraemia Impaired synacthen test Symptoms may develop before, with, or after neurological symptoms…

Addisonian features

  • Bronzed skin pigmentation
  • Scanty hair
  • Gastrointestinal disturbance
  • Fatigue
  • Hypotension
  • Hyponatraemia
  • Impaired synacthen test
  • Symptoms may develop before, with, or after neurological symptoms
  • They may precede neurological features by years

Other endocrine features

Features of female heterozygote carriers

Acronyms

References

  1. van Geel BM, Assies J, Wanders RJ, Barth PG. X linked adrenoleukodystrophy: clinical presentation, diagnosis, and therapy. JNNP 1997; 63:4-14.
  2. Das G, Baglioni P, Kadiyala R. Importance of family history in patients with adrenoleukodystrophy QJM 2010; 103:628-630.
  3. Engelen M, Barbier M, Dijkstra IM, et al. X-linked adrenoleukodystrophy in women: a cross-sectional cohort study. Brain 2014; 137:693-706.

Related checklists

Loading...